Search on: CALCIUM CHANNELS, L-TYPE 
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Descriptor English:   Calcium Channels, L-Type 
Descriptor Spanish:   Canales de Calcio Tipo L 
Descriptor Portuguese:   Canais de Cálcio Tipo L 
Synonyms English:   Dihydropyridine Receptor
L-Type Calcium Channel
L-Type VDCC
L-Type VDCC alpha-2 Subunit
L-Type VDCC beta Subunit
L-Type VDCC delta Subunit
L-Type VDCC gamma Subunit
L-Type Voltage-Dependent Calcium Channels
Calcium Channel, L-Type
Calcium Channels, L Type
Calcium Channels, Long-Lasting
L Type Calcium Channel
L Type Calcium Channels
L Type VDCC
L Type VDCC alpha 1 Subunit
L Type VDCC alpha 2 Subunit
L Type VDCC beta Subunit
L Type VDCC delta Subunit
L Type VDCC gamma Subunit
L Type Voltage Dependent Calcium Channels
Long Lasting Calcium Channels
Receptor, Dihydropyridine
VDCC, L-Type
Dihydropyridine Receptors
L-Type Calcium Channels
L-Type VDCC alpha-1 Subunit
Long-Lasting Calcium Channels
Receptors, Dihydropyridine  
Tree Number:   D12.776.157.530.400.150.400
D12.776.543.550.450.150.400
D12.776.543.585.400.150.400
Definition English:   Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites. 
Indexing Annotation English:   DF: VDCC L
History Note English:   2000; use L-TYPE CALCIUM CHANNELS (NM) 1993-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   34475 
Unique Identifier:   D020746 

Occurrence in VHL:
 

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